Zoledronic acid increases docetaxel cytotoxicity through pMEK and Mcl-1 inhibition in a hormone-sensitive prostate carcinoma cell line

Zoledronic acid increases docetaxel cytotoxicity through pMEK and Mcl-1 inhibition in a hormone-sensitive prostate carcinoma cell line

<p>Abstract</p> <p>Background</p> <p>In prostate cancer, the identification of drug combinations that could reduce the tumor cell population and rapidly eradicate hormone-resistant cells potentially present would be a remarkable breakthrough in the treatment of this dis...

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Bibliographic Details
Main Authors: Silvestrini Rosella, Tesei Anna, Vannini Ivan, Ulivi Paola, Carloni Silvia, Brigliadori Giovanni, Fabbri Francesco, Amadori Dino, Zoli Wainer
Format: Article
Language:English
Published: BMC 2008-08-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/6/1/43

Internet

http://www.translational-medicine.com/content/6/1/43

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