Transcriptomic analysis reveals distinct adaptive molecular mechanism in the hippocampal CA3 from rats susceptible or not-susceptible to hyperthermia-induced seizures

Abstract Febrile seizures during early childhood are a relevant risk factor for the development of mesial temporal lobe epilepsy. Nevertheless, the molecular mechanism induced by febrile seizures that render the brain susceptible or not-susceptible to epileptogenesis remain poorly understood. Becaus...

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Bibliographic Details
Main Authors: Silvia Y. Bando, Fernanda B. Bertonha, Pedro H. N. Menezes, André K. Takahara, Nathália A. Khaled, Paula Santos, Mara S. Junqueira, Roberto M. Cesar, Carlos A. Moreira-Filho
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-37535-w