Immunologic Biomarkers in Peripheral Blood of Persons With Tuberculosis and Advanced HIV

IntroductionTuberculosis (TB) is a common opportunistic infection among people living with HIV. Diagnostic tests such as culture, Xpert-MTB-RIF, and ULTRA have low sensitivity in paucibacillary TB disease; a blood biomarker could improve TB diagnostic capabilities. We assessed soluble factors to ide...

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Main Authors: Artur T. L. Queiroz, Mariana Araújo-Pereira, Beatriz Barreto-Duarte, Adriano Gomes-Silva, Allyson G. Costa, Alice M. S. Andrade, João Pedro Miguez-Pinto, Renata Spener-Gomes, Alexandra B. Souza, Aline Benjamin, Flavia Sant’Anna, Marina C. Figueiredo, Vidya Mave, Padmini Salgame, Jerrold J. Ellner, Timothy R. Sterling, Marcelo Cordeiro-dos-Santos, Bruno B. Andrade, Valeria C. Rolla
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.890003/full