2-Aminoimidazoles Inhibit <i>Mycobacterium abscessus</i> Biofilms in a Zinc-Dependent Manner

2-Aminoimidazoles Inhibit <i>Mycobacterium abscessus</i> Biofilms in a Zinc-Dependent Manner

Biofilm growth is thought to be a significant obstacle to the successful treatment of <i>Mycobacterium abscessus</i> infections. A search for agents capable of inhibiting <i>M. abscessus</i> biofilms led to our interest in 2-aminoimidazoles and related scaffolds, which have p...

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Bibliographic Details
Main Authors: Juan M. Belardinelli, Wei Li, Kevin H. Martin, Michael J. Zeiler, Elena Lian, Charlotte Avanzi, Crystal J. Wiersma, Tuan Vu Nguyen, Bhanupriya Angala, Vinicius C. N. de Moura, Victoria Jones, Bradley R. Borlee, Christian Melander, Mary Jackson
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Mycobacterium abscessus</i>
nontuberculous mycobacteria
biofilm
2-aminoimidazoles
zinc
Online Access:https://www.mdpi.com/1422-0067/23/6/2950

Internet

https://www.mdpi.com/1422-0067/23/6/2950

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