Myelin membrane assembly is driven by a phase transition of myelin basic proteins into a cohesive protein meshwork.

Myelin membrane assembly is driven by a phase transition of myelin basic proteins into a cohesive protein meshwork.

Rapid conduction of nerve impulses requires coating of axons by myelin. To function as an electrical insulator, myelin is generated as a tightly packed, lipid-rich multilayered membrane sheath. Knowledge about the mechanisms that govern myelin membrane biogenesis is required to understand myelin dis...

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Bibliographic Details
Main Authors: Shweta Aggarwal, Nicolas Snaidero, Gesa Pähler, Steffen Frey, Paula Sánchez, Markus Zweckstetter, Andreas Janshoff, Anja Schneider, Marie-Theres Weil, Iwan A T Schaap, Dirk Görlich, Mikael Simons
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3676292?pdf=render

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http://europepmc.org/articles/PMC3676292?pdf=render

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