CEP250 is Required for Maintaining Centrosome Cohesion in the Germline and Fertility in Male Mice

CEP250 is Required for Maintaining Centrosome Cohesion in the Germline and Fertility in Male Mice

Male gametogenesis involves both mitotic divisions to amplify germ cell progenitors that gradually differentiate and meiotic divisions. Centrosomal regulation is essential for both types of divisions, with centrioles remaining tightly paired during the interphase. Here, we generated and characterize...

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Bibliographic Details
Main Authors: Sandrine Floriot, Laura Bellutti, Johan Castille, Pauline Moison, Sébastien Messiaen, Bruno Passet, Laurent Boulanger, Abdelhak Boukadiri, Sophie Tourpin, Christian Beauvallet, Marthe Vilotte, Julie Riviere, Christine Péchoux, Maud Bertaud, Jean-Luc Vilotte, Gabriel Livera
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
centrosome
spermatogenesis
meiosis
DNA damage
oogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.754054/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.754054/full

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