Nutrient-stimulated insulin secretion in mouse islets is critically dependent on intracellular pH

<p>Abstract</p> <p>Background</p> <p>Many mechanistic steps underlying nutrient-stimulated insulin secretion (NSIS) are poorly understood. The influence of intracellular pH (pH<sub>i</sub>) on insulin secretion is widely documented, and can be used as an inv...

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Bibliographic Details
Main Authors: Gunawardana Subhadra C, Rocheleau Jonathan V, Head W Steven, Piston David W
Format: Article
Language:English
Published: BMC 2004-06-01
Series:BMC Endocrine Disorders
Online Access:http://www.biomedcentral.com/1472-6823/4/1