Functional roles of the N- and C-terminal regions of the human mitochondrial single-stranded DNA-binding protein.

Biochemical studies of the mitochondrial DNA (mtDNA) replisome demonstrate that the mtDNA polymerase and the mtDNA helicase are stimulated by the mitochondrial single-stranded DNA-binding protein (mtSSB). Unlike Escherichia coli SSB, bacteriophage T7 gp2.5 and bacteriophage T4 gp32, mtSSBs lack a lo...

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Bibliographic Details
Main Authors: Marcos T Oliveira, Laurie S Kaguni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2965674?pdf=render