A review on the research progress of traditional Chinese medicine with anti-cancer effect targeting ferroptosis

Abstract Ferroptosis is a non-apoptotic form of regulated cell death characterized by iron-dependent lipid peroxidation. It can be triggered by various mechanisms, including the glutathione peroxidase 4 (GPX4)-glutathione (GSH) axis, iron metabolism, lipid metabolism, the GTP cyclohydrolase 1 (GCH1)...

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Bibliographic Details
Main Authors: Longyan Wang, Huiming Huang, Xingxing Li, Lishan Ouyang, Xuejiao Wei, Jinxin Xie, Dongxiao Liu, Peng Tan, Zhongdong Hu
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Chinese Medicine
Subjects:
Online Access:https://doi.org/10.1186/s13020-023-00838-1