Acute toxicity analysis of an inhibitor of BCL2, Disarib, in rats

Abstract Apoptosis or programmed cell death is a highly regulated process, which eliminates unwanted and damaged cells. Inhibition of apoptosis is a hallmark of cancer cells. BCL2 family proteins are known to play a vital role in the regulation of apoptosis. Overexpression of BCL2, an antiapoptotic...

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Bibliographic Details
Main Authors: Shivangi Sharma, Kontham Kulangara Varsha, Ujjayinee Ray, Humaira Siddiqua, Anjana Elizabeth Jose, Sridhar Muninarasimaiah, Sathees C. Raghavan, Bibha Choudhary
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89387-x