Patterned mechanical feedback establishes a global myosin gradient

How does DNA encode shape? Here, via in toto light sheet microscopy and optogenetic control of cellular forces, the authors show that spatially patterned mechanical feedback loops establish the cytoskeletal patterns driving axis elongation tissue flow in Drosophila.

Bibliographic Details
Main Authors: Hannah J. Gustafson, Nikolas Claussen, Stefano De Renzis, Sebastian J. Streichan
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34518-9