Profiling molecular regulators of recurrence in chemorefractory triple-negative breast cancers

Profiling molecular regulators of recurrence in chemorefractory triple-negative breast cancers

Abstract Background Approximately two thirds of patients with localized triple-negative breast cancer (TNBC) harbor residual disease (RD) after neoadjuvant chemotherapy (NAC) and have a high risk-of-recurrence. Targeted therapeutic development for TNBC is of primary significance as no targeted thera...

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Bibliographic Details
Main Authors: Bradley A. Hancock, Yu-Hsiang Chen, Jeffrey P. Solzak, Mufti N. Ahmad, David C. Wedge, Dumitru Brinza, Charles Scafe, James Veitch, Rajesh Gottimukkala, Walt Short, Rutuja V. Atale, Mircea Ivan, Sunil S. Badve, Bryan P. Schneider, Xiongbin Lu, Kathy D. Miller, Milan Radovich
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Breast Cancer Research
Subjects:
Triple-negative
Breast
Cancer
Recurrence
Chemoresistance
Relapse
Online Access:http://link.springer.com/article/10.1186/s13058-019-1171-7

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http://link.springer.com/article/10.1186/s13058-019-1171-7

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