Unlocking the adenosine receptor mechanism of the tumour immune microenvironment

The suppressive tumour microenvironment significantly hinders the efficacy of immunotherapy in treating solid tumors. In this context, stromal cells, such as tumour-associated fibroblasts, undergo changes that include an increase in the number and function of immunosuppressive cells. Adenosine, a fa...

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Bibliographic Details
Main Authors: Yecheng Han, Chenshuang Dong, Mingwang Hu, Xinmiao Wang, Guiling Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1434118/full