Effects of indomethacin on prostanoid synthesis and vasomotor responsiveness in endothelium-denuded abdominal and thoracic aortas of Wistar rats

In endothelium-denuded abdominal (but not thoracic) aortas of rats, the nonselective cyclooxygenase (COX) inhibitor, indomethacin, suppressed contractions evoked by α-adrenergic agonists hypothetically mediated by prostanoids. We aimed to identify these non-endothelial-derived contractile prostanoid...

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Bibliographic Details
Main Authors: Ruth M. López, Janette E. López, Jorge S. López, María C. Castillo, Gustavo Guevara, José A. Morales, Oscar A. López, Jair Lozano, Enrique F. Castillo
Format: Article
Language:English
Published: Taylor & Francis Group 2017-04-01
Series:Clinical and Experimental Hypertension
Subjects:
Online Access:http://dx.doi.org/10.1080/10641963.2016.1226895