Design of a chitosan-based nano vaccine against epsilon toxin of Clostridium perfringens type D and evaluation of its immunogenicity in BALB/c mice

Design of a chitosan-based nano vaccine against epsilon toxin of Clostridium perfringens type D and evaluation of its immunogenicity in BALB/c mice

Background and purpose: Clostridium perfringens is an anaerobic, spore-forming, and pathogenic bacterium that causes intestinal diseases in humans and animals. In these cases, therapeutic intervention is challenging; because the disease progresses much rapidly. This bacterium can produce 5 main toxi...

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Bibliographic Details
Main Authors: Farnaz Poorhassan, Fahimeh Nemati, Parvaneh Saffarian, Seyed Ali Mirhosseini, Mohammad Javad Motamedi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
chitosan; clostridium perfringens; epsilon toxin; immunization; nano-vaccine.
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2021;volume=16;issue=6;spage=575;epage=585;aulast=Poorhassan

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http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2021;volume=16;issue=6;spage=575;epage=585;aulast=Poorhassan

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