Stilbene B10 induces apoptosis and tumor suppression in lymphoid Raji cells by BTK-mediated regulation of the KRAS/HDAC1/EP300/PEBP1 axis

Stilbene B10 induces apoptosis and tumor suppression in lymphoid Raji cells by BTK-mediated regulation of the KRAS/HDAC1/EP300/PEBP1 axis

Lymphoma is a cancer of the lymphoid cells that originated in matured B or T cells. The bioactive natural compounds can efficiently treat this disease with lesser side effects. Thus, in this study, a natural stilbene B10 (3-methoxy 5-hydroxy stilbene) isolated from Cajanus cajan (Pigeon Pea) was scr...

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Bibliographic Details
Main Authors: Krishnapriya M. Varier, Gou Dan, Wuling Liu, Guoping Wu, Chaoda Xiao, Huang Lei, Tao Ling, Yanping Jiang, Ying Chen, Yaacov Ben-David, Yanmei Li, Nenling Zhang, Babu Gajendran, Xiangchun Shen
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
BTK
EP300
Lymphoma
PEBP1
Raji
Stilbenes
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222012768

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http://www.sciencedirect.com/science/article/pii/S0753332222012768

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