Generation of a human induced pluripotent stem cell line overexpressing CCL22 with islet cells differentiation potential

CCL22 is a macrophage-derived immunosuppressive chemokine that recruits regulatory T cells through the CCL22:CCR4 axis, playing an important role in homeostatic and inflammatory responses. A CCL22-overexpressing human induced pluripotent stem cell line (CNNDi001-A-2) was generated by lentiviral tran...

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Bibliographic Details
Main Authors: Duan Jinliang, Bai Fang, Zhu Xiaofeng, He Xiaoshun, Hu Anbin
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S187350612300288X