Population pharmacokinetics of benznidazole in neonates, infants and children using a new pediatric formulation.

Population pharmacokinetics of benznidazole in neonates, infants and children using a new pediatric formulation.

<h4>Background</h4>There is a major need for information on pharmacokinetics (PK) of benznidazole (BNZ) in children with Chagas disease (CD). We conducted a multicentre population PK, safety and efficacy study in children, infants and neonates with CD treated with BNZ (formulated in 100...

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Bibliographic Details
Main Authors: Jaime Altcheh, Guillermo Moscatelli, Martin Caruso, Samanta Moroni, Margarita Bisio, Maria Rosa Miranda, Celia Monla, Maria Vaina, Maria Valdez, Lucrecia Moran, Teresa Ramirez, Oscar Ledesma Patiño, Adelina Riarte, Nicolas Gonzalez, Jayme Fernandes, Fabiana Alves, Isabela Ribeiro, Facundo Garcia-Bournissen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0010850

Internet

https://doi.org/10.1371/journal.pntd.0010850

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