The implications of oncolytic viruses targeting fibroblasts in enhancing the antitumoural immune response

Oncolytic viruses (OVs) are an emerging immunotherapy platform that selectively target tumour cells, inducing immunogenic cell death. This reverses the ‘immune-desert’ phenotype of tumours, enhancing antitumour immunity. However, oncolytic virotherapy has shown limited efficacy in solid tumours due...

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Bibliographic Details
Main Authors: Ibrahem Al-Obaidi, Ciaran Sandhu, Bilal Qureshi, Leonard W. Seymour
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024152358