The implications of oncolytic viruses targeting fibroblasts in enhancing the antitumoural immune response
Oncolytic viruses (OVs) are an emerging immunotherapy platform that selectively target tumour cells, inducing immunogenic cell death. This reverses the ‘immune-desert’ phenotype of tumours, enhancing antitumour immunity. However, oncolytic virotherapy has shown limited efficacy in solid tumours due...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-10-01
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Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024152358 |