Activation of Nrf2 by Esculetin Mitigates Inflammatory Responses through Suppression of NF-κB Signaling Cascade in RAW 264.7 Cells

Activation of Nrf2 by Esculetin Mitigates Inflammatory Responses through Suppression of NF-κB Signaling Cascade in RAW 264.7 Cells

Inflammation is a major root of several diseases such as allergy, cancer, Alzheimer’s, and several others, and the present state of existing drugs provoked researchers to search for new treatment strategies. Plants are regarded to be unique sources of active compounds holding pharmacological propert...

Full description

Bibliographic Details
Main Authors: Thanasekaran Jayakumar, Chun-Jen Huang, Ting-Lin Yen, Chih-Wei Hsia, Joen-Rong Sheu, Periyakali Saravana Bhavan, Wei-Chieh Huang, Cheng-Ying Hsieh, Chih-Hsuan Hsia
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Molecules
Subjects:
esculetin
NO/iNOS
MAPK/NF-κB
Nrf2
DPPH
anti-inflammation
Online Access:https://www.mdpi.com/1420-3049/27/16/5143

Internet

https://www.mdpi.com/1420-3049/27/16/5143

Similar Items