Avapritinib treatment of aggressive systemic mastocytosis with a novel KIT exon 17 mutation
Background: Systemic mastocytosis is a rare hematologic malignancy that leads to the accumulation of neoplastic mast cells in the bone marrow, visceral organs, and skin. Mutations in the receptor tyrosine kinase, KIT are seen in most patients with systemic mastocytosis. The most common mutation is a...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-01-01
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Series: | Leukemia Research Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213048923000493 |