Avapritinib treatment of aggressive systemic mastocytosis with a novel KIT exon 17 mutation

Background: Systemic mastocytosis is a rare hematologic malignancy that leads to the accumulation of neoplastic mast cells in the bone marrow, visceral organs, and skin. Mutations in the receptor tyrosine kinase, KIT are seen in most patients with systemic mastocytosis. The most common mutation is a...

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Bibliographic Details
Main Authors: Lyndsey Sandow, Ajia Town, Michael C. Heinrich
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Leukemia Research Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213048923000493