Oligomerized CARD16 promotes caspase‐1 assembly and IL‐1β processing

Oligomerized CARD16 promotes caspase‐1 assembly and IL‐1β processing

Increasing evidence indicates that caspase recruitment domain (CARD)‐mediated caspase‐1 (CASP1) assembly is an essential process for its activation and subsequent interleukin (IL)‐1β release, leading to the initiation of inflammation. Both CARD16 and CARD17 were previously reported as inhibitory hom...

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Bibliographic Details
Main Authors: Tadayoshi Karasawa, Akira Kawashima, Fumitake Usui, Hiroaki Kimura, Koumei Shirasuna, Yoshiyuki Inoue, Takanori Komada, Motoi Kobayashi, Yoshiko Mizushina, Junji Sagara, Masafumi Takahashi
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:FEBS Open Bio
Subjects:
Caspase
Cytokine
Inflammation
Interleukin
Online Access:https://doi.org/10.1016/j.fob.2015.04.011

Internet

https://doi.org/10.1016/j.fob.2015.04.011

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