Filamin A in platelets: Bridging the (signaling) gap between the plasma membrane and the actin cytoskeleton

Platelets are anucleate cells that are essential for hemostasis and wound healing. Upon activation of the cell surface receptors by their corresponding extracellular ligands, platelets undergo rapid shape change driven by the actin cytoskeleton; this shape change reaction is modulated by a diverse a...

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Bibliographic Details
Main Authors: Enoli De Silva, Felix Hong, Hervé Falet, Hugh Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.1060361/full