Antioxidant and Anticancer Functions of Protein Acyltransferase DHHC3

Silencing of DHHC3, an acyltransferase enzyme in the DHHC family, extensively upregulates oxidative stress (OS). Substrates for DHHC3-mediated palmitoylation include several antioxidant proteins and many other redox regulatory proteins. This helps to explain why DHHC3 ablation upregulates OS. DHHC3...

Full description

Bibliographic Details
Main Authors: Chandan Sharma, Martin E. Hemler
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/11/5/960