Wnt Signaling Pathway Collapse upon β-Catenin Destruction by a Novel Antimicrobial Peptide SKACP003: Unveiling the Molecular Mechanism and Genetic Activities Using Breast Cancer Cell Lines

Wnt Signaling Pathway Collapse upon β-Catenin Destruction by a Novel Antimicrobial Peptide SKACP003: Unveiling the Molecular Mechanism and Genetic Activities Using Breast Cancer Cell Lines

Despite progress in breast cancer treatment, the survival rate for patients with metastatic breast cancer remains low due to chemotherapeutic agent resistance and the lack of specificity of the current generation of cancer drugs. Our previous findings indicated that the antimicrobial peptide SKACP00...

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Bibliographic Details
Main Authors: Kanitha Selvarathinam, Prabhu Subramani, Malarvili Thekkumalai, Ravikumar Vilwanathan, Ramganesh Selvarajan, Akebe Luther King Abia
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
antimicrobial peptides
anticancer agents
breast cancer
Wnt pathway
β-catenin
downregulation
Online Access:https://www.mdpi.com/1420-3049/28/3/930

Internet

https://www.mdpi.com/1420-3049/28/3/930

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