Lupus Nephritis: Enigmas, Conflicting Models and an Emerging Concept
Abstract Autoantibodies to components of chromatin, which include double-stranded DNA (dsDNA), histones and nucleosomes, are central in the pathogenesis of lupus nephritis. How anti-chromatin autoantibodies exert their nephritogenic activity, however, is controversial. One model assumes that autoant...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2013-06-01
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| Series: | Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.2119/molmed.2013.00010 |