Cancer immunohistogram representing cancer-immunity cycle by immunohistochemistry predicts the efficacy of immune checkpoint inhibitors in urological cancer patients

Abstract We developed an immunohistogram representing an individual cancer-immunity cycle based on immunohistochemical analyses. We evaluated its ability to predict the efficacy of immune checkpoint inhibitors (ICI) in 11 patients with urothelial carcinoma and 7 patients with renal cell carcinoma wh...

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Bibliographic Details
Main Authors: Toshiki Kijima, Terufumi Kubo, Daisaku Nishihara, Akinori Nukui, Yoshihiko Hirohashi, Toshihiko Torigoe, Takao Kamai
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-14700-1