A Nucleus-Targeting WT1 Antagonistic Peptide Encapsulated in Polymeric Nanomicelles Combats Refractory Chronic Myeloid Leukemia

A Nucleus-Targeting WT1 Antagonistic Peptide Encapsulated in Polymeric Nanomicelles Combats Refractory Chronic Myeloid Leukemia

Chronic myeloid leukemia (CML) is recognized as a classic clonal myeloproliferative disorder. Given the limited treatment options for CML patients in the accelerated phase (AP) and blast phase (BP), there is an evident need to develop new therapeutic strategies. This has the potential to improve out...

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Bibliographic Details
Main Authors: Mengting Chen, Xiaocui Fang, Rong Du, Jie Meng, Jingyi Liu, Mingpeng Liu, Yanlian Yang, Chen Wang
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Pharmaceutics
Subjects:
nucleus-targeting
antagonistic peptide
leukemia
nanomicelle
WT1
Online Access:https://www.mdpi.com/1999-4923/15/9/2305

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https://www.mdpi.com/1999-4923/15/9/2305

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