Long non-coding RNA ZEB1-AS1 regulates miR-200b/FSCN1 signaling and enhances migration and invasion induced by TGF-β1 in bladder cancer cells

Long non-coding RNA ZEB1-AS1 regulates miR-200b/FSCN1 signaling and enhances migration and invasion induced by TGF-β1 in bladder cancer cells

Abstract Background The effect of competing endogenous RNA (ceRNA) can regulate gene expression by competitively binding microRNAs. Fascin-1 (FSCN1) plays an important role in the regulation of cellular migration and invasion during tumor progression, but how its regulatory mechanism works through t...

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Bibliographic Details
Main Authors: Ruxu Gao, Naiwen Zhang, Jianyu Yang, Yuyan Zhu, Zhe Zhang, Jianfeng Wang, Xiaolong Xu, Zeliang Li, Xiankui Liu, Zhenhua Li, Jun Li, Chuize Kong, Jianbin Bi
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Bladder cancer
fascin1
Long non-coding RNA ZEB1-AS1
microRNA miR-200b
TGF-β1
Online Access:http://link.springer.com/article/10.1186/s13046-019-1102-6

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http://link.springer.com/article/10.1186/s13046-019-1102-6

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