Design of Targeted Flurbiprofen Biomimetic Nanoparticles for Management of Arthritis: In Vitro and In Vivo Appraisal

Design of Targeted Flurbiprofen Biomimetic Nanoparticles for Management of Arthritis: In Vitro and In Vivo Appraisal

Flurbiprofen (FLUR) is a potent non-steroidal anti-inflammatory drug used for the management of arthritis. Unfortunately, its therapeutic effect is limited by its rapid clearance from the joints following intra-articular injection. To improve its therapeutic efficacy, hyaluronic acid-coated bovine s...

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Bibliographic Details
Main Authors: Hagar I. Mohamed, Amal H. El-Kamel, Ghada O. Hammad, Lamia A. Heikal
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Pharmaceutics
Subjects:
arthritis
flurbiprofen
nanoparticles
intra-articular
hyaluronic acid
active targeting
Online Access:https://www.mdpi.com/1999-4923/14/1/140

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https://www.mdpi.com/1999-4923/14/1/140

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