Pharmacokinetics and Pharmacodynamics of Cenerimod, A Selective S1P1R Modulator, Are Not Affected by Ethnicity in Healthy Asian and White Subjects

Cenerimod is a sphingosine‐1‐phosphate 1 receptor (S1P1R) modulator in phase II development for treatment of systemic lupus erythematosus. Its pharmacokinetics (PKs), pharmacodynamics (PDs), as well as safety and tolerability were investigated in white and Asian subjects to allow for recruitment of...

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Bibliographic Details
Main Authors: Pierre‐Eric Juif, Jasper Dingemanse, Peter Winkle, Mike Ufer
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.12873