Quantification of zinc intoxication of Candida glabrata after phagocytosis by primary macrophages

Summary: Zinc (Zn2+) is a trace element, playing pivotal roles during host-pathogen interactions. Macrophages can sequester Zn2+ and restrict bioavailability or increase phagolysosomal Zn2+ to kill pathogens. This method quantifies Zn2+-mediated clearance of the human fungal pathogen C. glabrata aft...

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Bibliographic Details
Main Authors: Philipp Penninger, Michael Riedelberger, Irina Tsymala, Hossein Arzani, Sabrina Jenull, Karl Kuchler
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721000599