Genetically engineered probiotics as catalytic glucose depriver for tumor starvation therapy

Genetically engineered probiotics as catalytic glucose depriver for tumor starvation therapy

Cancer cells predominantly adapt the frequent but less efficient glycolytic process to produce ATPs rather than the highly efficient oxidative phosphorylation pathway. Such a regulated metabolic pattern in cancer cells offers promising therapeutic opportunities to kill tumors by glucose depletion or...

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Bibliographic Details
Main Authors: Penghao Ji, Bolin An, Zhongming Jie, Liping Wang, Shuwen Qiu, Changhao Ge, Qihui Wu, Jianlin Shi, Minfeng Huo
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Materials Today Bio
Subjects:
Metabolic intervention
Tumor targeting
Programmable living biomaterials
Glucose deprivation
Autophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006422003131

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http://www.sciencedirect.com/science/article/pii/S2590006422003131

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