Umbelliprenin via increase in the MECP2 and attenuation of oxidative stress mitigates the autistic-like behaviors in mouse model of maternal separation stress

Umbelliprenin via increase in the MECP2 and attenuation of oxidative stress mitigates the autistic-like behaviors in mouse model of maternal separation stress

Introduction: Autism spectrum disorder (ASD) is a complex neurodevelopmental condition. Maternal separation (MS) stress is an early-life stress factor associated with behaviors resembling Autism. Both MECP2 and oxidative stress are implicated in the pathophysiology of Autism. Umbelliprenin (UMB) is...

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Detalles Bibliográficos
Autores principales: Parnian Karimi, Mehryar Shahgholian Ghahfarroki, Zahra Lorigooini, Mehrdad Shahrani, Hossein Amini-Khoei
Formato: Artículo
Lenguaje:English
Publicado: Frontiers Media S.A. 2024-01-01
Colección:Frontiers in Pharmacology
Materias:
maternal separation stress
Autism spectrum disorder
umbelliprenin
MeCP2
oxidative stress
Acceso en línea:https://www.frontiersin.org/articles/10.3389/fphar.2023.1300310/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1300310/full

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