Umbelliprenin via increase in the MECP2 and attenuation of oxidative stress mitigates the autistic-like behaviors in mouse model of maternal separation stress

Umbelliprenin via increase in the MECP2 and attenuation of oxidative stress mitigates the autistic-like behaviors in mouse model of maternal separation stress

Introduction: Autism spectrum disorder (ASD) is a complex neurodevelopmental condition. Maternal separation (MS) stress is an early-life stress factor associated with behaviors resembling Autism. Both MECP2 and oxidative stress are implicated in the pathophysiology of Autism. Umbelliprenin (UMB) is...

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Bibliographic Details
Main Authors: Parnian Karimi, Mehryar Shahgholian Ghahfarroki, Zahra Lorigooini, Mehrdad Shahrani, Hossein Amini-Khoei
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Pharmacology
Subjects:
maternal separation stress
Autism spectrum disorder
umbelliprenin
MeCP2
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1300310/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1300310/full

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