Specific Antibody and the T-Cell Response Elicited by BNT162b2 Boosting After Two ChAdOx1 nCoV-19 in Common Variable Immunodeficiency

Specific Antibody and the T-Cell Response Elicited by BNT162b2 Boosting After Two ChAdOx1 nCoV-19 in Common Variable Immunodeficiency

Common variable immunodeficiency (CVID) patients have markedly decreased immune response to vaccinations. In this study we evaluated humoral and T cell-mediated responses against severe acute respiratory syndrome coronavirus-2 (SARS-Cov-2) with additional flow cytometric changes in CVID patients rec...

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Bibliographic Details
Main Authors: Vera Goda, Gergely Kriván, Andrea Kulcsár, Márton Gönczi, Szabolcs Tasnády, Zsolt Matula, Ginette Nagy, Gabriella Bekő, Máté Horváth, Ferenc Uher, Zoltán Szekanecz, István Vályi-Nagy
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
common variable immunodeficiency (CVID)
primary immunodeficiency
anti-SARS-CoV-2 antibodies
IFN-γ producing T cells
IFN-γ ELISpot assay
vaccination
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.907125/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.907125/full

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