Specific Antibody and the T-Cell Response Elicited by BNT162b2 Boosting After Two ChAdOx1 nCoV-19 in Common Variable Immunodeficiency

Specific Antibody and the T-Cell Response Elicited by BNT162b2 Boosting After Two ChAdOx1 nCoV-19 in Common Variable Immunodeficiency

Common variable immunodeficiency (CVID) patients have markedly decreased immune response to vaccinations. In this study we evaluated humoral and T cell-mediated responses against severe acute respiratory syndrome coronavirus-2 (SARS-Cov-2) with additional flow cytometric changes in CVID patients rec...

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Bibliographic Details
Main Authors:	Vera Goda, Gergely Kriván, Andrea Kulcsár, Márton Gönczi, Szabolcs Tasnády, Zsolt Matula, Ginette Nagy, Gabriella Bekő, Máté Horváth, Ferenc Uher, Zoltán Szekanecz, István Vályi-Nagy
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-06-01
Series:	Frontiers in Immunology
Subjects:	common variable immunodeficiency (CVID) primary immunodeficiency anti-SARS-CoV-2 antibodies IFN-γ producing T cells IFN-γ ELISpot assay vaccination
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.907125/full

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