A Novel four-way complex variant translocation involving chromosome 46, XY, t(4;9; 19;22)(q25:q34;p13.3;q11.2) in a chronic myeloid leukemia patient

A Novel four-way complex variant translocation involving chromosome 46, XY, t(4;9; 19;22)(q25:q34;p13.3;q11.2) in a chronic myeloid leukemia patient

Philadelphia (Ph) chromosome (9; 22)(q34;q11) is well established in more than 90% of chronic myeloid leukemia (CML) patients and the remaining 5-8% CML patients show variant and complex translocations, with the involvement of third, fourth or fifth chromosome other then 9;22. However, in very rare...

Full description

Bibliographic Details
Main Authors: Muhammad eAsif, Mohammad Sarwar eJamal, Abdul Rehman Khan, Muhammad Imran Naseer, Abrar eHussain, Hani eChoudhry, Arif eMalik, Shahida Aziz Khan, Maged eMostafa, Ashraf eAli, Saima eIram, Kashif eKamran, Asim eIqbal, Zainularifeen eAbduljaleel, Peter Natesan Pushparaj, Mahmood eRasool
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Oncology
Subjects:
Philadelphia Chromosome
Chronic myeloid leukemia
BCR-ABL gene
complex variant translocation
Four way ranslocation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00124/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00124/full

Similar Items