Transient inactivation of the medial prefrontal cortex affects both anxiety and decision-making in male Wistar rats
In both humans and rats high levels of anxiety impair decision-making in the Iowa Gambling Task (IGT) in male subjects. Expression of the immediate early gene c-fos as marker of neural activity in rat studies indicated a role of the medial prefrontal cortex (prelimbic and infralimbic region; mPFC) i...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2011-09-01
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| Series: | Frontiers in Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnins.2011.00102/full |