Transient inactivation of the medial prefrontal cortex affects both anxiety and decision-making in male Wistar rats

Transient inactivation of the medial prefrontal cortex affects both anxiety and decision-making in male Wistar rats

In both humans and rats high levels of anxiety impair decision-making in the Iowa Gambling Task (IGT) in male subjects. Expression of the immediate early gene c-fos as marker of neural activity in rat studies indicated a role of the medial prefrontal cortex (prelimbic and infralimbic region; mPFC) i...

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Bibliographic Details
Main Authors:	Leonie ede Visser, Annemarie eBaars, Jose evan 't Klooster, Ruud evan den Bos
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2011-09-01
Series:	Frontiers in Neuroscience
Subjects:	Anxiety Rats decision-making Medial prefrontal cortex
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fnins.2011.00102/full

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