Evaluation of Proteoforms of the Transmembrane Chemokines CXCL16 and CX3CL1, Their Receptors, and Their Processing Metalloproteinases ADAM10 and ADAM17 in Proliferative Diabetic Retinopathy

Evaluation of Proteoforms of the Transmembrane Chemokines CXCL16 and CX3CL1, Their Receptors, and Their Processing Metalloproteinases ADAM10 and ADAM17 in Proliferative Diabetic Retinopathy

The transmembrane chemokine pathways CXCL16/CXCR6 and CX3CL1/CX3CR1 are strongly implicated in inflammation and angiogenesis. We investigated the involvement of these chemokine pathways and their processing metalloproteinases ADAM10 and ADAM17 in the pathophysiology of proliferative diabetic retinop...

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Bibliographic Details
Main Authors: Ahmed M. Abu El-Asrar, Mohd Imtiaz Nawaz, Ajmal Ahmad, Alexandra De Zutter, Mohammad Mairaj Siddiquei, Marfa Blanter, Eef Allegaert, Priscilla W. Gikandi, Gert De Hertogh, Jo Van Damme, Ghislain Opdenakker, Sofie Struyf
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
proliferative diabetic retinopathy
chemokines
metalloproteinases
CXCL16
CX3CL1
ADAM10
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.601639/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.601639/full

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