Evaluation of the effectiveness and safety of oral vancomycin versus placebo in the prevention of recurrence of Clostridioides difficile infection in patients under systemic antibiotic therapy: a phase III, randomised, double-blind clinical trial

Evaluation of the effectiveness and safety of oral vancomycin versus placebo in the prevention of recurrence of Clostridioides difficile infection in patients under systemic antibiotic therapy: a phase III, randomised, double-blind clinical trial

Introduction Clostridioides difficile infection (CDI) is the most prevalent cause of nosocomial bacterial diarrhoea and it is strongly associated with antibiotic use. The recurrence of CDI is a growing medical problem. Data from real-life studies and one open label randomised clinical trial (RCT) su...

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Bibliographic Details
Main Authors: Mario Fernandez-Ruiz, Julia Origüen, José M Aguado, David Lora, Rafael San-Juan, Alejandro Callejas-Diaz, Karen Campion, Beatriz Diaz-Pollan, Giancarlo Candela, Maria Angeles Orellana, Irene Llorente Muñoz, Maria Teresa Garcia, Maite Martinez-Uña, Jose Miguel Ferrari
Format: Article
Language:English
Published: BMJ Publishing Group 2023-09-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/9/e072121.full

Internet

https://bmjopen.bmj.com/content/13/9/e072121.full

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