Energy expenditure in myelofibrosis patients treated with a JAK1/2 inhibitor

Weight gain is a known adverse effect of ruxolitinib, a JAK1/2 inhibitor that is the mainstay of treatment for many patients with myelofibrosis. The mechanisms behind weight increase with ruxolitinib is incompletely understood, although decreased adipose tissue lipolysis and increased appetite due t...

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Bibliographic Details
Main Authors: Douglas Tremblay, Mikaela Dougherty, John Mascarenhas, Emily Jane Gallagher
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1141029/full