The antigen processing-associated transporter gene polymorphism: Role on gene and protein expression in HPV-infected pre-cancerous cervical lesion

Human papillomavirus (HPV) is the major pathogen for cervical lesions. The evasion mechanism of the immune response and persistence of HPV infection can be influenced by polymorphisms (SNPs) in genes associated with transporter associated with antigen processing (TAP), which may change the peptide b...

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Main Authors: Fernanda Silva Medeiros, Mauro César da Silva, Neila Caroline Henrique da Silva, Thailany Thays Gomes, Renan Garcia Gomes, Larissa Albuquerque Paiva, Fabiana Oliveira dos Santos Gomes, Christina Alves Peixoto, Maria Carolina Valença Rygaard, Stefan Welkovic, Maria Luiza Bezerra Menezes, Eduardo Antônio Donadi, Norma Lucena-Silva
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.979800/full