Optimized quantification of intra-host viral diversity in SARS-CoV-2 and influenza virus sequence data

Optimized quantification of intra-host viral diversity in SARS-CoV-2 and influenza virus sequence data

ABSTRACT High error rates of viral RNA-dependent RNA polymerases lead to diverse intra-host viral populations during infection. Errors made during replication that are not strongly deleterious to the virus can lead to the generation of minority variants. However, accurate detection of minority varia...

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Bibliographic Details
Main Authors: A. E. Roder, K. E. E. Johnson, M. Knoll, M. Khalfan, B. Wang, S. Schultz-Cherry, S. Banakis, A. Kreitman, C. Mederos, J.-H. Youn, R. Mercado, W. Wang, M. Chung, D. Ruchnewitz, M. I. Samanovic, M. J. Mulligan, M. Lässig, M. Luksza, S. Das, D. Gresham, E. Ghedin
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mBio
Subjects:
SARS-CoV-2
influenza
genomics
bioinformatics
Online Access:https://journals.asm.org/doi/10.1128/mbio.01046-23

Internet

https://journals.asm.org/doi/10.1128/mbio.01046-23

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