An introduction to PIWI-interacting RNAs (piRNAs) in the context of metazoan small RNA silencing pathways

PIWI proteins and their associated PIWI-interacting RNAs (piRNAs) constitute a small RNA-based adaptive immune system that restricts the deleterious activity of mobile genetic elements to protect genome integrity. Self/nonself discrimination is at the very core of successful defence and relies on co...

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Bibliographic Details
Main Author: Astrid D. Haase
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:RNA Biology
Subjects:
Online Access:http://dx.doi.org/10.1080/15476286.2022.2132359