An introduction to PIWI-interacting RNAs (piRNAs) in the context of metazoan small RNA silencing pathways
PIWI proteins and their associated PIWI-interacting RNAs (piRNAs) constitute a small RNA-based adaptive immune system that restricts the deleterious activity of mobile genetic elements to protect genome integrity. Self/nonself discrimination is at the very core of successful defence and relies on co...
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Format: | Article |
Language: | English |
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Taylor & Francis Group
2022-12-01
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Series: | RNA Biology |
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Online Access: | http://dx.doi.org/10.1080/15476286.2022.2132359 |