Cytoplasm-translocated Ku70/80 complex sensing of HBV DNA induces hepatitis-associated chemokine secretion
Chronic hepatitis B remains a serious disease, mainly owing to the severe pathological consequences of persistent hepatitis B virus (HBV) infection of carriers, which is difficult to cure using current therapies. When the immune system responds to hepatocytes experiencing rapid HBV replication, effe...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-12-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00569/full |