Systems View of Deconditioning During Spaceflight Simulation in the PlanHab Project: The Departure of Urine 1 H-NMR Metabolomes From Healthy State in Young Males Subjected to Bedrest Inactivity and Hypoxia

Systems View of Deconditioning During Spaceflight Simulation in the PlanHab Project: The Departure of Urine 1 H-NMR Metabolomes From Healthy State in Young Males Subjected to Bedrest Inactivity and Hypoxia

We explored the metabolic makeup of urine in prescreened healthy male participants within the PlanHab experiment. The run-in (5 day) and the following three 21-day interventions [normoxic bedrest (NBR), hypoxic bedrest (HBR), and hypoxic ambulation (HAmb)] were executed in a crossover manner within...

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Bibliographic Details
Main Authors: Robert Šket, Leon Deutsch, Zala Prevoršek, Igor B. Mekjavić, Janez Plavec, Joern Rittweger, Tadej Debevec, Ola Eiken, Blaz Stres
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Physiology
Subjects:
urine
metabolome
NMR
inactivity
interplanetary travel
medicine
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2020.532271/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2020.532271/full

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