Prevalence of <i>ARID1A</i> Mutations in Cell-Free Circulating Tumor DNA in a Cohort of 71,301 Patients and Association with Driver Co-Alterations

<i>ARID1A</i> abnormalities disturb transcriptional processes regulated by chromatin remodeling and correlate with immunotherapy responsiveness. We report the first blood-based cell-free DNA (cfDNA) next-generation sequencing (NGS) <i>ARID1A</i> analysis. From November 2016 t...

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Bibliographic Details
Main Authors: Razelle Kurzrock, Charu Aggarwal, Caroline Weipert, Lesli Kiedrowski, Jonathan Riess, Heinz-Josef Lenz, David Gandara
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/17/4281