Statistical Classification for Raman Spectra of Tumoral Genomic DNA

Statistical Classification for Raman Spectra of Tumoral Genomic DNA

We exploit Surface-Enhanced Raman Scattering (SERS) to investigate aqueous droplets of genomic DNA deposited onto silver-coated silicon nanowires, and we show that it is possible to efficiently discriminate between spectra of tumoral and healthy cells. To assess the robustness of the proposed techni...

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Bibliographic Details
Main Authors: Claudio Durastanti, Emilio N. M. Cirillo, Ilaria De Benedictis, Mario Ledda, Antonio Sciortino, Antonella Lisi, Annalisa Convertino, Valentina Mussi
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Micromachines
Subjects:
tumoral genomic DNA
Raman spectroscopy
classification
principal component analysis
logistic regression
minimum distance classifiers
Online Access:https://www.mdpi.com/2072-666X/13/9/1388

Internet

https://www.mdpi.com/2072-666X/13/9/1388

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