Nonspecific Amyloid Aggregation of Chicken Smooth-Muscle Titin: In Vitro Investigations

Nonspecific Amyloid Aggregation of Chicken Smooth-Muscle Titin: In Vitro Investigations

A giant multidomain protein of striated and smooth vertebrate muscles, titin, consists of tandems of immunoglobulin (Ig)- and fibronectin type III (FnIII)-like domains representing β-sandwiches, as well as of disordered segments. Chicken smooth muscles express several titin isoforms of ~500–1500 kDa...

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Bibliographic Details
Main Authors: Alexander G. Bobylev, Elmira I. Yakupova, Liya G. Bobyleva, Nikolay V. Molochkov, Alexander A. Timchenko, Maria A. Timchenko, Hiroshi Kihara, Alexey D. Nikulin, Azat G. Gabdulkhakov, Tatiana N. Melnik, Nikita V. Penkov, Michail Y. Lobanov, Alexey S. Kazakov, Miklós Kellermayer, Zsolt Mártonfalvi, Oxana V. Galzitskaya, Ivan M. Vikhlyantsev
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
smooth muscle titin
protein aggregates
amyloid aggregation
amyloids
cross-β
Online Access:https://www.mdpi.com/1422-0067/24/2/1056

Internet

https://www.mdpi.com/1422-0067/24/2/1056

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